Supplements To Prevent Skin Cancer – Vitamin A is an essential nutrient for good health, but does taking it help reduce the risk of skin cancer? A new study finds a link between vitamin A intake and a lower risk of skin cancer.
One vitamin that humans need to stay healthy is vitamin A, which supports growth and development, as well as eye health, reproductive health, and skin health.
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Vitamin A is found in animal products such as eggs, chicken, turkey or beef liver. Animal-derived vitamin A is called retinol.
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This vitamin is also found in many fruits and vegetables in the form of beta-carotene, alpha-carotene, and beta-cryptoxanthin. Some fruits and vegetables that are rich in vitamin A include sweet potatoes, carrots, kale, butternut squash, pumpkin, broccoli, apricots, and papaya, among others.
By taking dietary supplements, although adult men should not consume more than 900 micrograms of this vitamin per day, adult women should not consume more than 700 micrograms per day.
Now, a study from the Warren Alpert Medical School and Brown School of Public Health in Providence, Rhode Island, Harvard Medical School in Boston, Massachusetts, and Inje University in Seoul, South Korea, investigates the effects of vitamin A Does intake affect the risk of cutaneous squamous cell carcinoma, one of the most common forms of skin cancer. Research results published in journal
According to the Skin Cancer Foundation, a nonprofit and advocacy group, “squamous cell carcinoma is the second most common form of skin cancer,” with doctors diagnosing more than 1 million new cases each year in the United States alone.
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Because this cancer is so common, it’s important to find better prevention strategies to lower people’s risk of developing it.
In the current study (lead author is Dr. Jongwoo Kim), researchers sought to find out whether there was any link between vitamin A and carotenoid intake and a reduced risk of cutaneous squamous cell carcinoma.
The team analyzed data from 75,170 women (mean age 50.4 years) who participated in the Nurses’ Health Study and 48,400 men (mean age 54.3 years) who participated in the Health Professionals Follow-up Study.
Over 26 years of follow-up, researchers documented a total of 3,978 cases of skin cancer among participants in both study groups.
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The researchers were also able to find information about the participants’ vitamin A intake through detailed surveys that participants in both study groups filled out approximately every 4 years.
According to their analysis, the researchers found that participants with higher vitamin A intake had a lower risk of developing cutaneous squamous cell carcinoma.
“In this large prospective study of U.S. women and men, we found that higher total vitamin A, retinol, and multiple carotenoids including beta-cryptoxanthin, lycopene, lutein, and zeaxanthin ) intake was associated with a lower risk of squamous cell carcinoma],” the researchers wrote in their research paper.
The researchers added that in these cases, most of the vitamin A came from food sources, especially vegetables, rather than dietary supplements.
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While the researchers note that their findings are a good start in understanding whether dietary factors influence skin cancer risk, they acknowledge that the study faces some limitations.
The authors specifically noted the “homogeneity of the study population,” which consisted almost exclusively of white, educated health professionals. To conduct studies that are more inclusive and have more generalizable results, researchers should focus on more diverse populations, they say.
“However,” the study authors wrote, “the changes in vitamin A intake [in the study group] were favorable,” adding that “skin cancer is less common in non-whites.”
One study author also reported a potential conflict of interest, having served as a consultant to the biopharmaceutical companies AbbVie and Amgen, Janssen, Merck, Novartis and Pfizer, as well as the Centers for Disease Control and Prevention (CDC).
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Although the study methodology may be flawed, the researchers concluded that the findings to date support the idea that adequate vitamin A intake may help prevent the development of skin cancer:
“We found an inverse association between vitamin A and carotenoid intake and the risk of skin [squamous cell carcinoma], which supports a protective role of vitamin A in the development of [squamous cell carcinoma]. Our data further supports the idea that supplementation and dietary vitamin A may help prevent [squamous cell carcinoma].” The experts at Cornerstone Dermatology and Surgery Group are dedicated to providing you with the latest evidence-based information and treatments for your All skin health concerns. We hope our blog posts help you learn new things you can use in your daily life. Between visits to your trusted provider during your visit to Cornerstone! Any specific questions related to care can be fully addressed by appointment.
The good news is that the pill exists, and for people at high risk for non-melanoma skin cancer, reducing the chance of skin cancer coming back is as simple as taking a twice-daily supplement.
This supplement is called niacinamide and is a water-soluble form of vitamin B3. Niacinamide supplementation reduced the incidence of new squamous cell carcinoma and basal skin cancer by 23% compared with placebo, according to results from a Phase 3 clinical study published in 2015 in the New England Journal of Medicine.
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David Fieleke, MD, FAAD, board-certified dermatologist and Mohs surgeon at Cornerstone Dermatology in Lee’s Summit, says this encouraging study provides a simple, actionable step for patients at high risk for non-melanoma skin cancers .
“Nicotinamide is easily available, fairly cheap, and often has no significant side effects,” he said. “I recommend that patients at high risk for skin cancer purchase this supplement wherever they shop for groceries or at their local pharmacy and take 500 milligrams twice daily based on research.”
Ultraviolet rays from the sun can cause DNA damage. Certain antioxidants, such as nicotinamide, can help reverse this damage to some extent, Filek said.
Not only did the study show a decrease in the incidence of basal cell carcinoma and squamous cell carcinoma, it also reduced patients’ risk of developing actinic keratosis, a common precancerous skin condition.
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“This supplement reduces the immune suppression caused by UV radiation, allowing our skin to adapt and repair damage before it turns into malignant skin cancer,” he said. “We hope to be able to prevent more skin cancers in the future.”
Yes, if you are at high risk for skin cancer (previous skin cancer, precancerous lesions, and sun damage), you can go ahead and add niacinamide to your cart. But be careful, you will get
“Make sure you’re not buying niacin, another form of vitamin B3, which can have some unwanted side effects, such as flushing, increased blood pressure and headaches,” Fieleke says.
Fieleke said it’s also important to understand that niacinamide is not an oral sunscreen, and all patients should continue to use appropriate sun protection.
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“Nicotinamide supplementation is another important tool in our prevention of skin cancer,” he said. “But taking birth control pills does not replace the proven advice of a dermatologist. We still need to be vigilant about applying sunscreen, wearing sun-protective clothing and avoiding peak sun exposure times during the day.”
If you’re having trouble finding niacinamide at your local grocery store or pharmacy, you can find several good options online. Here are examples of the right supplements to buy when shopping online: Today, most people are wary of sun exposure because science has revealed a link between the sun’s UV rays and skin cancer. For example, the average person spending an afternoon at the beach slathers on sunscreen, preferably one with an SPF of at least 30-45, and sits under an umbrella. For many of us, tanned skin doesn’t look as attractive as it did in the 1970s/80s.
But what if you’ve already had a bout with skin cancer, especially a non-melanoma type like squamous cell carcinoma or basal cell carcinoma? People who already have one of these skin cancers are at greater risk of developing other cancers, including melanoma, a more dangerous form of skin cancer. If this applies to you, don’t worry. No need to pull up the covers and stay in bed all day. You have several options to help prevent skin cancer from coming back.
Professionals say the best strategy is to protect your skin as much as possible by wearing UV-protective clothing, using sunscreen every day, avoiding prolonged sun exposure, and visiting your skin cancer doctor for yearly checkups. However, if you want more, try a vitamin B3 (niacin) supplement such as niacinamide.
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For years, vitamins have been promoted as near-miraculous elixirs that can cure a variety of diseases and medical conditions, and the supplement market is worth billions of dollars. you can not
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